Creation and application of immortalized bait libraries for targeted enrichment and next-generation sequencing
نویسندگان
چکیده
منابع مشابه
Creation and application of immortalized bait libraries for targeted enrichment and next-generation sequencing.
Since the introduction of next-generation sequencing, several techniques have been developed to selectively enrich and sequence specific parts of the genome at high coverage. These techniques include enzymatic methods employing molecular inversion probes, PCR based approaches, hybrid capture, and in-solution capture. In-solution capture employs RNA probes transcribed from a pool of DNA template...
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ژورنال
عنوان ژورنال: BioTechniques
سال: 2012
ISSN: 0736-6205,1940-9818
DOI: 10.2144/0000113877